PlumX Metrics
Embed PlumX Metrics

Whole Animal Feeding FLat (WAFFL): a complete and comprehensive validation of a novel, high-throughput fly experimentation system

G3: Genes, Genomes, Genetics, ISSN: 2160-1836, Vol: 13, Issue: 3
2023
  • 2
    Citations
  • 0
    Usage
  • 13
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Most Recent News

Data on Genetics Reported by Researchers at Department of Embryology [Whole Animal Feeding Flat (Waffl): a Complete and Comprehensive Validation of a Novel, High-throughput Fly Experimentation System]

2023 MAR 07 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Life Science Daily -- Current study results on Life Sciences - Genetics

Article Description

Non-mammalian model organisms have been essential for our understanding of the mechanisms that control development, disease, and physiology, but they are underutilized in pharmacological and toxicological phenotypic screening assays due to their low throughput in comparison with cell-based screens. To increase the utility of using Drosophila melanogaster in screening, we designed the Whole Animal Feeding FLat (WAFFL), a novel, flexible, and complete system for feeding, monitoring, and assaying flies in a high-throughput format. Our 3D printed system is compatible with inexpensive and readily available, commercial 96-well plate consumables and equipment. Experimenters can change the diet at will during the experiment and video record for behavior analysis, enabling precise dosing, measurement of feeding, and analysis of behavior in a 96-well plate format.

Bibliographic Details

Maria D L A Jaime; Ghadi H Salem; Daniel J Martinez; Sean Karott; Alejandra Flores; Cameron D Palmer; Sharvani Mahadevaraju; Jonathan Krynitsky; Marcial Garmendia-Cedillos; Sarah Anderson; Susan Harbison; Thomas J Pohida; William B Ludington; Brian Oliver; J Tennessen

Oxford University Press (OUP)

Biochemistry, Genetics and Molecular Biology; Medicine

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know