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A graphical algorithm for fast computation of identity coefficients and generalized kinship coefficients

Bioinformatics, ISSN: 1367-4803, Vol: 25, Issue: 12, Page: 1561-1563
2009
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Article Description

Computing the probability of identity by descent sharing among n genes given only the pedigree of those genes is a computationally challenging problem, if n or the pedigree size is large. Here, I present a novel graphical algorithm for efficiently computing all generalized kinship coefficients for n genes. The graphical description transforms the problem from doing many recursion on the pedigree to doing a single traversal of a structure referred to as the kinship graph. © The Author 2009. Published by Oxford University Press. All rights reserved.

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