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Association screening of common and rare genetic variants by penalized regression

Bioinformatics, ISSN: 1367-4803, Vol: 26, Issue: 19, Page: 2375-2382
2010
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Motivation: This article extends our recent research on penalized estimation methods in genome-wide association studies to the realm of rare variants. Results: The new strategy is tested on both simulated and real data. Our findings on breast cancer data replicate previous results and shed light on variant effects within genes. © The Author 2010. Published by Oxford University Press. All rights reserved.

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