PlumX Metrics
Embed PlumX Metrics

The role of inflammation in HPV carcinogenesis

Carcinogenesis, ISSN: 0143-3334, Vol: 31, Issue: 11, Page: 1905-1912
2010
  • 144
    Citations
  • 0
    Usage
  • 216
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Most Recent News

Prevalence of high-risk human papillomavirus genotypes and viral load correlated with squamous cell inflammation among women in Gabon

Abstract Background High-risk genotypes of Human Papillomavirus are responsible for 90% of cases of cervical cancer worldwide. Inflammation of squamous cells is mainly linked to

Review Description

The role of inflammation in human papillomavirus (HPV) infection and disease is complex since it involves responses capable of preventing initial infections, clearing those ongoing as well as promoting persistence and progression of associated lesions. Avoiding the immune response has been considered a key aspect of HPV persistence which is the main factor leading to HPV-related neoplasia. HPVs have evolved different ways of targeting immune signaling pathways. Moreover, host inflammatory response may promote lesion progression and affect tumor fate by diverse mechanisms including the direct participation of inflammatory cells. In this review, we discuss the interplay between HPV oncogenic proteins and an array of inflammatory responses that ultimately may lead to cancer. © The Author 2010. Published by Oxford University Press. All rights reserved.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know