Detection of infectious influenza virus in cough aerosols generated in a simulated patient examination room
Clinical Infectious Diseases, ISSN: 1058-4838, Vol: 54, Issue: 11, Page: 1569-1577
2012
- 160Citations
- 197Captures
- 5Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations160
- Citation Indexes150
- 150
- CrossRef120
- Policy Citations9
- Policy Citation9
- Clinical Citations1
- PubMed Guidelines1
- Captures197
- Readers197
- 197
- Mentions5
- News Mentions3
- News3
- Blog Mentions2
- Blog2
Most Recent News
Maximizing Fit for Cloth and Medical Procedure Masks to Improve Performance and Reduce SARS-CoV-2 Transmission and Exposure, 2021
On February 10, 2021, this report was posted online as an MMWR Early Release. Please note:. This report has been corrected. John T. Brooks, MD1;
Article Description
Background.The potential for aerosol transmission of infectious influenza virus (ie, in healthcare facilities) is controversial. We constructed a simulated patient examination room that contained coughing and breathing manikins to determine whether coughed influenza was infectious and assessed the effectiveness of an N95 respirator and surgical mask in blocking transmission.Methods.National Institute for Occupational Safety and Health aerosol samplers collected size-fractionated aerosols for 60 minutes at the mouth of the breathing manikin, beside the mouth, and at 3 other locations in the room. Total recovered virus was quantitated by quantitative polymerase chain reaction and infectivity was determined by the viral plaque assay and an enhanced infectivity assay.Results.Infectious influenza was recovered in all aerosol fractions (5.0% in >4 μm aerodynamic diameter, 75.5% in 1-4 μm, and 19.5% in <1 μm; n = 5). Tightly sealing a mask to the face blocked entry of 94.5% of total virus and 94.8% of infectious virus (n = 3). A tightly sealed respirator blocked 99.8% of total virus and 99.6% of infectious virus (n = 3). A poorly fitted respirator blocked 64.5% of total virus and 66.5% of infectious virus (n = 3). A mask documented to be loosely fitting by a PortaCount fit tester, to simulate how masks are worn by healthcare workers, blocked entry of 68.5% of total virus and 56.6% of infectious virus (n = 2).Conclusions.These results support a role for aerosol transmission and represent the first reported laboratory study of the efficacy of masks and respirators in blocking inhalation of influenza in aerosols. The results indicate that a poorly fitted respirator performs no better than a loosely fitting mask. © 2012 The Author.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84861038567&origin=inward; http://dx.doi.org/10.1093/cid/cis237; http://www.ncbi.nlm.nih.gov/pubmed/22460981; https://academic.oup.com/cid/article-lookup/doi/10.1093/cid/cis237; https://dx.doi.org/10.1093/cid/cis237; https://academic.oup.com/cid/article/54/11/1569/321689
Oxford University Press (OUP)
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