Chronotropic incompetence and mortality in middle-aged men with known or suspected coronary heart disease
European Heart Journal, ISSN: 0195-668X, Vol: 29, Issue: 15, Page: 1896-1902
2008
- 43Citations
- 28Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations43
- Citation Indexes42
- 42
- CrossRef24
- Policy Citations1
- Policy Citation1
- Captures28
- Readers28
- 28
Article Description
Aims: The objective is to study whether a heart rate (HR) increase from 40 to 100% of maximal work capacity in the exercise test (HR40-100) independently predicts mortality in men with known or suspected coronary heart disease (CHD). Methods and results: The subjects were 294 men, 42-61 years of age, from eastern Finland with known or suspected CHD but without use of HR-lowering medication at baseline. HR was measured at rest and during a maximal, symptom-limited exercise test. During an average follow-up of 11.0 years, there were 61 all-cause deaths. In Cox-multivariable model, mortality increased by 41% (95% confidence interval, 12-79%) with a 1-SD (15 b.p.m.) decrement in HR40-100. HR increase from rest to 40% of maximal work capacity was not associated with an increased risk of death. Synergism was observed between HR40-100 and workload achieved at HR of 100 b.p.m. so that men having low values for both these HR variables had a particularly adverse prognosis compared with men with high values for these variables. Conclusion: An attenuated HR increase particularly during the latter half of a maximal exercise test is an independent predictor of death in men with known or suspected CHD. © The Author 2008.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=48749109209&origin=inward; http://dx.doi.org/10.1093/eurheartj/ehn269; http://www.ncbi.nlm.nih.gov/pubmed/18556711; https://academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehn269; https://dx.doi.org/10.1093/eurheartj/ehn269; https://academic.oup.com/eurheartj/article/29/15/1896/510734
Oxford University Press (OUP)
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