The Evolution of Amitraz and Its Metabolic Degradation Products in Human Blood over 90 Days for Use in Forensic Determination
Journal of Analytical Toxicology, ISSN: 1945-2403, Vol: 45, Issue: 9, Page: 937-942
2021
- 2Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Captures2
- Readers2
Article Description
Amitraz is a pesticide that is often involved in poisoning cases. In determination process of poisoning cases, a problem often encountered is that when the evidence samples were examined, the poison had already decomposed, thus posing significant difficulty for obtaining evidences. In this study, we qualitatively and quantitatively tracked the metabolic degradation products of amitraz and ascertained that the metabolic degradation products were N,N'-bisdimethylphenylformamidine, N'-(2,4-dimethylphenyl)-N-methylformamidine (DMPF), 2,4-dimethylformamidine (DMF) and 2,4-dimethylaniline (DMA). It was found that although amitraz decomposed rather rapidly, the metabolic degradation products of amitraz persisted for quite a long time. This study demonstrates that forensic evidence in poisoning cases of amitraz can be obtained by the determination of DMPF, DMF and DMA. This study can provide insights on obtaining forensic evidences in poisoning cases.
Bibliographic Details
Oxford University Press (OUP)
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