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Genome sequence and assembly of bos indicus

Journal of Heredity, ISSN: 0022-1503, Vol: 103, Issue: 3, Page: 342-348
2012
  • 84
    Citations
  • 0
    Usage
  • 138
    Captures
  • 3
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    84
  • Captures
    138
  • Mentions
    3
    • Blog Mentions
      1
      • Blog
        1
    • News Mentions
      1
      • News
        1
    • References
      1
      • Wikipedia
        1

Most Recent Blog

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Introduction However, the underlying genetic factors (including genes, regulatory elements and DNA sequence polymorphisms) contributing to phenotypic traits selected during and after cattle domestication remain largely unknown (Elsik et al., 2009; Canavez et al., 2012; Kemper and Goddard, 2012; Womack, 2012; Gutierrez-Gil et al., 2015; Utsunomiya et al., 2015). Many studies have highlighted the im

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Invited review: African indigenous cattle: unique genetic resources in a rapidly changing world

  INTRODUCTION            Once humans started domesticating animals, livestock populations have continually been influenced through selective breeding in response to the needs of the owners as well

Article Description

Cattle are divided into 2 groups referred to as taurine and indicine, both of which have been under strong artificial selection due to their importance for human nutrition. A side effect of this domestication includes a loss of genetic diversity within each specialized breed. Recently, the first taurine genome was sequenced and assembled, allowing for a better understanding of this ruminant species. However, genetic information from indicine breeds has been limited. Here, we present the first genome sequence of an indicine breed (Nellore) generated with 52X coverage by SOLiD sequencing platform. As expected, both genomes share high similarity at the nucleotide level for all autosomes and the X chromosome. Regarding the Y chromosome, the homology was considerably lower, most likely due to uncompleted assembly of the taurine Y chromosome. We were also able to cover 97% of the annotated taurine protein-coding genes. © 2012 The American Genetic Association.

Bibliographic Details

Canavez, Flavio C; Luche, Douglas D; Stothard, Paul; Leite, Katia R M; Sousa-Canavez, Juliana M; Plastow, Graham; Meidanis, João; Souza, Maria Angélica; Feijao, Pedro; Moore, Steve S; Camara-Lopes, Luiz H

Oxford University Press (OUP)

Biochemistry, Genetics and Molecular Biology; Medicine

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