Interactions between γδT cells and neutrophils in cancer: knowns and unknowns

The tumor microenvironment provides a unique opportunity to gain insight into the relationship and crosstalk between different cell types. In this context, little is known about the interaction between γδT cells and neutrophils, which are innate immune cells abundant in the tumor microenvironment. Interestingly, both γδT cells and neutrophils are heterogeneous, may play diverse regulatory roles, and have been shown to have both protumor and antitumor functions. In this editorial, we discuss recent advances in the understanding of interplay between γδT cells and neutrophils in cancer and provide insights and future directions highlighting the role these interactions may play in cancer.