A Case of Massive Fetal-Maternal Hemorrhage: Lessons Learned in Diagnosis and Treatment
Lab Medicine, ISSN: 1943-7730, Vol: 54, Issue: 3, Page: 333-336
2023
- 3Captures
- 1Mentions
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- Captures3
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Reports Outline Alloimmunization Research from University of Texas Medical Branch (A Case of Massive Fetal-Maternal Hemorrhage: Lessons Learned in Diagnosis and Treatment)
2022 NOV 15 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Drug Daily -- New research on alloimmunization is the subject of a
Article Description
The use of Rho(D) immune globulin in Rh-negative pregnant women has become standard of care, but many practicing clinicians do not know the dosing recommendations for this essential medication. In this article, we describe a case of a 15-year-old girl who presented with intrauterine fetal demise and was found to have massive fetomaternal hemorrhage. Kleihauer-Betke testing results indicated nearly 460 mL of fetal blood in the maternal circulation. The patient ultimately received 4800 μg of Rho(D) immune globulin, a dose that required close coordination with the obstetrical service and pharmacy. Although this is an unusual case of large-volume, potentially chronic, fetomaternal hemorrhage, it is also an excellent illustration of the principles for diagnosing this condition, as well as providing dosing guidelines for Rho(D) immunoglobulin to prevent alloimmunization.
Bibliographic Details
Oxford University Press (OUP)
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