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Co-infection of mammarenaviruses in a wild mouse, Tanzania

Virus Evolution, ISSN: 2057-1577, Vol: 8, Issue: 2, Page: veac065
2022
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Article Description

Mammarenaviruses are bi-segmented RNA viruses. They encompass viruses responsible for several severe diseases in humans. While performing a de novo assembly of a new virus found in a wild single-striped grass mouse in Tanzania, we found a single S but two divergent L segments. Natural co-infections, common within reptarenaviruses in captivity, were never reported for mammarenaviruses and never in a wild sample. This finding can have implications for virus evolution as co-infection could trigger viral recombination/reassortment in natural reservoirs.

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