Octopamine modulates ionic currents and spiking in dorsal unpaired median (DUM) neurons
NeuroReport, ISSN: 0959-4965, Vol: 8, Issue: 17, Page: 3737-3741
1997
- 31Citations
- 17Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations31
- Citation Indexes31
- 31
- CrossRef24
- Captures17
- Readers17
- 17
Article Description
MODULATORY effects of octopamine on ionic currents and spiking in isolated cockroach dorsal unpaired median neurons were investigated by means of the chopped voltage-/current-clamp and the patch-clamp technique. Octopamine increased the spiking frequency at concentrations ≤ 10 μM and reduced it at > 10 μM. It enhanced a low voltage-activated Ca current at 1 to 100 μM. At concentrations up to 10 μM two components of Ca- activated K current were potentiated. At > 10 μM octopamine in addition reduced a high voltage-activated Ca current and the Ca-activated K current. A membrane permeant cAMP-analogue imitated the effects obtained at high octopamine concentration. Octopamine and cAMP in addition reduced a depolarizing resting current at both low and high concentration. Possible mechanisms and physiological significance are discussed for the opposite effects of octopamine observed at low versus high concentrations.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0031466892&origin=inward; http://dx.doi.org/10.1097/00001756-199712010-00016; http://www.ncbi.nlm.nih.gov/pubmed/9427361; http://journals.lww.com/00001756-199712010-00016; https://dx.doi.org/10.1097/00001756-199712010-00016; https://insights.ovid.com/crossref?an=00001756-199712010-00016
Ovid Technologies (Wolters Kluwer Health)
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