Maternal-fetal transfer of anti-N-methyl-d-aspartate receptor antibodies
Obstetrics and Gynecology, ISSN: 1873-233X, Vol: 125, Issue: 5, Page: 1056-1058
2015
- 24Citations
- 70Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations24
- Citation Indexes24
- 24
- CrossRef17
- Captures70
- Readers70
- 70
Article Description
BACKGROUND: Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a neuroautoimmune disease commonly associated with ovarian teratomas. It is characterized by neuropsychiatric symptoms, seizures, and autonomic instability. Few cases are described in pregnancy, and little is known about potential fetal effects. CASE: Anti-NMDA receptor encephalitis was diagnosed at 24 weeks of gestation. No improvement occurred with intravenous immunoglobulin, methylprednisolone, and plasmapheresis. Imaging was unremarkable. Cesarean delivery with concurrent bilateral oophorectomy resulted in prompt maternal improvement. Antibody titers were positive in cord blood. CONCLUSION: Anti-N-methyl-d-aspartate receptor encephalitis in pregnancy can lead to NMDA receptor antibodies in the fetal circulation. Pregnancy interruption through early delivery with or without oophorectomy may accelerate maternal recovery.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84928170841&origin=inward; http://dx.doi.org/10.1097/aog.0000000000000548; http://www.ncbi.nlm.nih.gov/pubmed/25710615; http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00006250-201505000-00007; https://journals.lww.com/00006250-201505000-00007; http://dx.doi.org/10.1097/AOG.0000000000000548; https://dx.doi.org/10.1097/AOG.0000000000000548; https://journals.lww.com/greenjournal/Abstract/2015/05000/Maternal_Fetal_Transfer_of.7.aspx
Ovid Technologies (Wolters Kluwer Health)
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