Neuroimaging of HIV-associated neurocognitive disorders (HAND)
Current Opinion in HIV and AIDS, ISSN: 1746-6318, Vol: 9, Issue: 6, Page: 545-551
2014
- 70Citations
- 121Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations70
- Citation Indexes69
- 69
- CrossRef50
- Policy Citations1
- Policy Citation1
- Captures121
- Readers121
- 121
Review Description
Purpose of review HIV enters the brain after initial infection, and with time can lead to HIV-associated neurocognitive disorders (HAND). Although the introduction of combination antiretroviral therapy has reduced the more severe forms of HAND, milder forms are still highly prevalent. The 'gold standard' for HAND diagnosis remains detailed neuropsychological performance testing but additional biomarkers (including neuroimaging) may assist in early detection of HAND. Recent findings We review the application of recently developed noninvasive MRI and PET techniques in HIV+ individuals. In particular, magnetic resonance spectroscopy may be more sensitive than conventional MRI alone in detecting HIV associated changes. Diffusion tensor imaging has become increasingly popular for assessing changes in white matter structural integrity due to HIV. Both functional MRI and PET have been limitedly performed but could provide keys for characterizing neuropathophysiologic changes due to HIV. Summary It is hoped that continued progress will allow novel neuroimaging methods to be included in future HAND management guidelines.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84925497003&origin=inward; http://dx.doi.org/10.1097/coh.0000000000000112; http://www.ncbi.nlm.nih.gov/pubmed/25250553; http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=01222929-201411000-00008; http://journals.lww.com/01222929-201411000-00008; https://dx.doi.org/10.1097/coh.0000000000000112; https://insights.ovid.com/article/01222929-201411000-00008
Ovid Technologies (Wolters Kluwer Health)
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