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Heat shock proteins are important mediators of skeletal muscle insulin sensitivity

Exercise and Sport Sciences Reviews, ISSN: 0091-6331, Vol: 39, Issue: 1, Page: 34-42
2011
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Article Description

Endogenous heat shock proteins (HSP) are decreased in disease states associated with insulin resistance and aging. Induction of HSPs has been shown to decrease oxidative stress, inhibit inflammatory pathways, and enhance metabolic characteristics in skeletal muscle. As such, HSPs have the potential to function as an important defense system against the development of insulin resistance and type 2 diabetes. Copyright © 2010 by the American College of Sports Medicine.

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