Effect of probiotics on lipid profiles and blood pressure in patients with type 2 diabetes: A meta-analysis of RCTs
Medicine (United States), ISSN: 1536-5964, Vol: 96, Issue: 51, Page: e9166
2017
- 88Citations
- 109Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations88
- Citation Indexes86
- 86
- CrossRef39
- Policy Citations2
- Policy Citation2
- Captures109
- Readers109
- 109
Review Description
Background: This meta-analysis aimed to systematically evaluate the effects of probiotics on blood lipid and blood pressure among patients with type 2 diabetes mellitus (T2DM) based on the randomized controlled studies. Methods: PubMed, Cochrane, Embase, Wanfang, China National Knowledge Infrastructure, and VIP database were searched by the index words to identify the qualified randomized control trial. The latest research was done in the January 2017. Mean difference (MD) along with 95% confidence interval (CI) was used to analyze the included outcomes. Results: Ten trials were included at last with 297 patients in the treatment group and 294 patients in the control group. Probiotics significantly decreased the value of total cholesterol (SMD-0.57, 95% CI-0.92 to 0.21), triglyceride (SMD-0.66, 95% CI-0.93 to 0.39), low-density lipoprotein (SMD-0.40, 95% CI-0.79 to 0.01), systolic blood pressure (WMD-5.04, 95% CI-8.8 to 1.20), diastolic blood pressure (SMD-0.39, 95% CI-0.62 to 0.17), fasting blood glucose (FBG) (SMD 3.54, 95% CI 1.94-5.15) compared with the placebo treatment. Apart from this, probiotics could significantly improve the value of high-density lipoprotein (SMD 0.38, 95% CI 0.03-0.73). Conclusion: Probiotics may decrease the indexes of lipid profile, blood pressure, and FBG in patients with T2DM; application of probiotics might be a new method for lipid profiles and blood pressure management in T2DM.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85039699152&origin=inward; http://dx.doi.org/10.1097/md.0000000000009166; http://www.ncbi.nlm.nih.gov/pubmed/29390450; http://Insights.ovid.com/crossref?an=00005792-201712220-00037; https://journals.lww.com/00005792-201712220-00037; https://dx.doi.org/10.1097/md.0000000000009166; https://journals.lww.com/md-journal/Fulltext/2017/12220/Effect_of_probiotics_on_lipid_profiles_and_blood.37.aspx
Ovid Technologies (Wolters Kluwer Health)
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