Chitosan as a bone scaffold biomaterial
Journal of Craniofacial Surgery, ISSN: 1536-3732, Vol: 29, Issue: 7, Page: 1788-1793
2018
- 33Citations
- 4Usage
- 84Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations33
- Citation Indexes33
- 33
- CrossRef27
- Usage4
- Abstract Views4
- Captures84
- Readers84
- 84
Article Description
The current standard of care for bone reconstruction, whether secondary to injury, nonunion, cancer resection, or idiopathic bone loss, is autologous bone grafting. Alternatives to autograft and allograft bone substitutes currently being researched are synthetic and natural graft materials that are able to guide bone regeneration. One promising material currently being researched is chitosan, a highly versatile, naturally occurring polysaccharide, derived from the exoskeleton of arthropods that is comprised of glucosamine and N-acetylglucosamine. Research on chitosan as a bone scaffold has been promising. Chitosan is efficacious in bone regeneration due to its lack of immunogenicity, its biodegradability, and its physiologic features. Chitosan combined with growth factors and/or other scaffold materials has proven to be an effective alternative to autologous bone grafts. Additionally, current studies have shown that it can provide the additional benefit of a local drug delivery system. As research in the area of bone scaffolding continues to grow, further clinical research on chitosan in conjunction with growth factors, proteins, and alloplastic materials will likely be at the forefront.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85054437473&origin=inward; http://dx.doi.org/10.1097/scs.0000000000004909; http://www.ncbi.nlm.nih.gov/pubmed/30157141; https://journals.lww.com/00001665-201810000-00028; https://digitalcommons.memphis.edu/facpubs/12272; https://digitalcommons.memphis.edu/cgi/viewcontent.cgi?article=13271&context=facpubs; https://dx.doi.org/10.1097/scs.0000000000004909; https://journals.lww.com/jcraniofacialsurgery/Abstract/2018/10000/Chitosan_as_a_Bone_Scaffold_Biomaterial.28.aspx
Ovid Technologies (Wolters Kluwer Health)
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