PlumX Metrics
Embed PlumX Metrics

New opportunities for targeting the androgen receptor in prostate cancer

Cold Spring Harbor Perspectives in Medicine, ISSN: 2157-1422, Vol: 8, Issue: 12
2018
  • 22
    Citations
  • 0
    Usage
  • 49
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

Recent genomic analyses of metastatic prostate cancer have provided important insight into adaptive changes in androgen receptor (AR) signaling that underpin resistance to androgen deprivation therapies. Novel strategies are required to circumvent these AR-mediated resistance mechanisms and thereby improve prostate cancer survival. In this review, we present a summary of AR structure and function and discuss mechanisms of AR-mediated therapy resistance that represent important areas of focus for the development of new therapies.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know