Brain mechanisms of extinction of the classically conditioned eyeblink response
Learning and Memory, ISSN: 1072-0502, Vol: 11, Issue: 5, Page: 517-524
2004
- 67Citations
- 104Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations67
- Citation Indexes67
- 67
- CrossRef57
- Captures104
- Readers104
- 104
Review Description
It is well established that the cerebellum and its associated circuitry are essential for classical conditioning of the eyeblink response and other discrete motor responses (e.g., limb flexion, head turn, etc.) learned with an aversive unconditioned stimulus (US). However, brain mechanisms underlying extinction of these responses are still relatively unclear. Behavioral studies have demonstrated extinction as an active learning process distinct from acquisition. Experimental data in eyeblink conditioning suggest that plastic changes specific to extinction may play an important role in this process. Both cerebellar and hippocampal systems may be involved in extinction of these memories. The nature of this phenomenon and identification of the neural substrates necessary for extinction of originally learned responses is the topic of this review.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=4644236944&origin=inward; http://dx.doi.org/10.1101/lm.80004; http://www.ncbi.nlm.nih.gov/pubmed/15466302; http://learnmem.cshlp.org/lookup/doi/10.1101/lm.80004; https://dx.doi.org/10.1101/lm.80004; https://learnmem.cshlp.org/content/11/5/517
Cold Spring Harbor Laboratory
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