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A high-efficiency and clogging-free microfluidic device for size-selective cell separation

MHS 2017 - 28th 2017 International Symposium on Micro-NanoMechatronics and Human Science, Vol: 2018-January, Page: 1-2
2017
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Conference Paper Description

We developed a highly efficient and clogging-free cells separation microfluidic chip based on their size and deformability. Currently, cells separation is categorized either by hydrodynamic or using filtration. Hydrodynamic cell separation manipulates flow for separation process based on cell size. Whereas filtration technique with microstructure constriction to separate the cells based on size and deformability which is known in relation to cell phenotypes. However, size based separation techniques suffer from clogging and fouling issues.

Bibliographic Details

Anas Mohd Noor; Wu Lei; Taisuke Masuda; Koji Horio; Fumihito Arai; Toshiki Saito; Yasuhiko Miyata

Institute of Electrical and Electronics Engineers (IEEE)

Biochemistry, Genetics and Molecular Biology; Engineering

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