The biosynthetic genes for clavulanic acid and cephamycin production occur as a 'super-cluster' in three Streptomyces
FEMS Microbiology Letters, ISSN: 1574-6968, Vol: 110, Issue: 2, Page: 239-242
1993
- 99Citations
- 45Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations99
- Citation Indexes99
- 99
- CrossRef55
- Captures45
- Readers45
- 45
Article Description
The cosmid cloning vector pHC79 has been used to clone fragments of chromosomal DNA from the Streptomyces: S. clavuligerus, S. jumonjinensis and S. katsurahamanus. These strains all produce both the β-lactam antibiotic, cephamycin and the β-lactamase inhibitor, clavulanic acid. Although structurally related these two β-lactams are known to be derived from different biosynthetic precursors. Hybridisation studies and restriction mapping have shown that the gene clusters encoding the two biosynthetic pathways are chromosomally adjacent in these strains, thus creating a 'super-cluster' of genes involved in both the production and enhancement of activity of a β-lactam antibiotic. © 1993.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0027289141&origin=inward; http://dx.doi.org/10.1111/j.1574-6968.1993.tb06326.x; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85046521168&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/8349096; https://academic.oup.com/femsle/article-lookup/doi/10.1111/j.1574-6968.1993.tb06326.x; http://doi.wiley.com/10.1016/0378-1097(93)90472-E; http://dx.doi.org/10.1016/0378-1097(93)90472-e; http://dx.doi.org/10.1016/0378-1097%2893%2990472-e; https://dx.doi.org/10.1016/0378-1097%2893%2990472-e; https://academic.oup.com/femsle/article/110/2/239/534897; https://dx.doi.org/10.1111/j.1574-6968.1993.tb06326.x
Oxford University Press (OUP)
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know