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Earlier intervention in type 2 diabetes: The case for achieving early and sustained glycaemic control

International Journal of Clinical Practice, ISSN: 1368-5031, Vol: 59, Issue: 11, Page: 1309-1316
2005
  • 52
    Citations
  • 0
    Usage
  • 48
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    52
    • Citation Indexes
      49
    • Policy Citations
      2
      • Policy Citation
        2
    • Clinical Citations
      1
      • PubMed Guidelines
        1
  • Captures
    48

Review Description

In type 2 diabetes, the onset and progression of complications is significantly delayed by improving glycaemic control. However, the proportion of patients reaching and sustaining guideline recommendations for glycaemic targets remains unacceptably low. Recent clinical trials and predictive physiologically based mathematical simulations (Archimedes model) indicate that benefits can be enhanced with earlier intervention and timely achievement of glycaemic targets. This article reviews the evidence for early intervention, showing that intensive approaches, including earlier introduction of combination therapy, allow more patients to achieve glycaemic targets and hence reduce complications and delay disease progression. © Blackwell Publishing Ltd, 2005.

Bibliographic Details

Clifford J. Bailey; Stefano Del Prato; D. Eddy; Bernard Zinman; George Albetti; P. Pablo Aschner; Lawrence Blonde; Anne Marie Felton; Barry Goldstein; Ramon Gomis; Edward Horton; James LaSalle J.; Hong Kyu Lee; Lawrence Leiter; Stephan Matthaei; Marg McGill; Neil Munro; Richard Nesto; Paul Zimmet

Hindawi Limited

Medicine

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