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Focal infrared neural stimulation with high-field functional MRI: A rapid way to map mesoscale brain connectomes

Science Advances, ISSN: 2375-2548, Vol: 5, Issue: 4, Page: eaau7046
2019
  • 56
    Citations
  • 0
    Usage
  • 81
    Captures
  • 4
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    56
    • Citation Indexes
      56
  • Captures
    81
  • Mentions
    4
    • News Mentions
      3
      • 3
    • References
      1
      • 1

Most Recent News

A Quicker Way to Map the Brain's Connections

Scientists have discovered a new method for quickly and efficiently mapping the vast network of connections among neurons in the brain. Researchers combined infrared laser

Article Description

We have developed a way to map brain-wide networks using focal pulsed infrared neural stimulation in ultrahigh-field magnetic resonance imaging (MRI). The patterns of connections revealed are similar to those of connections previously mapped with anatomical tract tracing methods. These include connections between cortex and subcortical locations and long-range cortico-cortical connections. Studies of local cortical connections reveal columnar-sized laminar activation, consistent with feed-forward and feedback projection signatures. This method is broadly applicable and can be applied to multiple areas of the brain in different species and across different MRI platforms. Systematic point-by-point application of this method may lead to fundamental advances in our understanding of brain connectomes.

Bibliographic Details

Xu, Augix Guohua; Qian, Meizhen; Tian, Feiyan; Xu, Bin; Friedman, Robert M; Wang, Jianbao; Song, Xuemei; Sun, Yi; Chernov, Mykyta M; Cayce, Jonathan M; Jansen, E Duco; Mahadevan-Jansen, Anita; Zhang, Xiaotong; Chen, Gang; Roe, Anna Wang

American Association for the Advancement of Science (AAAS)

Multidisciplinary

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