Individual cell migration serves as the driving force for optic vesicle evagination
Science, ISSN: 0036-8075, Vol: 313, Issue: 5790, Page: 1130-1134
2006
- 162Citations
- 163Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations162
- Citation Indexes162
- CrossRef162
- 151
- Captures163
- Readers163
- 163
Article Description
The cellular mechanisms underlying organ formation are largely unknown. We visualized early vertebrate eye morphogenesis at single-cell resolution by in vivo imaging in medaka (Oryzios latipes). Before optic vesicle evagination, retinal progenitor cells (RPCs) modulate their convergence in a fate-specific manner. Presumptive forebrain cells converge toward the midline, whereas medial RPCs remain stationary, predetermining the site of evagination. Subsequent optic vesicle evagination is driven by the active migration of individual RPCs. The analysis of mutants demonstrated that the retina-specific transcription factor rx3 determines the convergence and migration behaviors of RPCs. Hence, the migration of individual cells mediates essential steps of organ morphogenesis.
Bibliographic Details
10.1126/science.1127144; 10.3410/f.1040359.493982; 10.3410/f.1040359.496421; 10.3410/f.1040359.489319; 10.3410/f.1040359.497027; 10.3410/f.1040359.489458
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33748084400&origin=inward; http://dx.doi.org/10.1126/science.1127144; http://www.ncbi.nlm.nih.gov/pubmed/16931763; https://facultyopinions.com/prime/1040359#eval493982; http://dx.doi.org/10.3410/f.1040359.493982; https://facultyopinions.com/prime/1040359#eval496421; http://dx.doi.org/10.3410/f.1040359.496421; https://facultyopinions.com/prime/1040359#eval489319; http://dx.doi.org/10.3410/f.1040359.489319; https://facultyopinions.com/prime/1040359#eval497027; http://dx.doi.org/10.3410/f.1040359.497027; https://www.science.org/doi/10.1126/science.1127144; https://facultyopinions.com/prime/1040359#eval489458; http://dx.doi.org/10.3410/f.1040359.489458; https://dx.doi.org/10.1126/science.1127144; https://www.science.org/lookup/doi/10.1126/science.1127144; https://science.sciencemag.org/content/313/5790/1130; https://science.sciencemag.org/content/313/5790/1130.abstract; https://science.sciencemag.org/content/sci/313/5790/1130.full.pdf; http://science.sciencemag.org/content/313/5790/1130; http://science.sciencemag.org/content/313/5790/1130.abstract; http://science.sciencemag.org/content/313/5790/1130.full.pdf; http://www.sciencemag.org/cgi/doi/10.1126/science.1127144; http://f1000.com/1040359#eval489458; http://f1000.com/1040359#eval496421; http://f1000.com/1040359#eval497027; http://f1000.com/1040359#eval493982; http://f1000.com/1040359#eval489319; https://www.science.org/doi/abs/10.1126/science.1127144
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