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Host-gut microbiota metabolic interactions

Science, ISSN: 1095-9203, Vol: 336, Issue: 6086, Page: 1262-1267
2012
  • 3,688
    Citations
  • 0
    Usage
  • 3,903
    Captures
  • 53
    Mentions
  • 28
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    3,688
    • Citation Indexes
      3,682
    • Policy Citations
      4
      • Policy Citation
        4
    • Patent Family Citations
      2
      • Patent Families
        2
  • Captures
    3,903
  • Mentions
    53
    • News Mentions
      51
      • News
        51
    • Blog Mentions
      1
      • Blog
        1
    • References
      1
      • Wikipedia
        1
  • Social Media
    28
    • Shares, Likes & Comments
      28
      • Facebook
        28

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Review Description

The composition and activity of the gut microbiota codevelop with the host from birth and is subject to a complex interplay that depends on the host genome, nutrition, and life-style. The gut microbiota is involved in the regulation of multiple host metabolic pathways, giving rise to interactive host-microbiota metabolic, signaling, and immune-inflammatory axes that physiologically connect the gut, liver, muscle, and brain. A deeper understanding of these axes is a prerequisite for optimizing therapeutic strategies to manipulate the gut microbiota to combat disease and improve health.

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