Pre-Bötzinger complex: A brainstem region that may generate respiratory rhythm in mammals
Science, ISSN: 0036-8075, Vol: 254, Issue: 5032, Page: 726-729
1991
- 1,785Citations
- 520Captures
- 16Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations1,785
- Citation Indexes1,784
- 1,784
- CrossRef1,668
- Academic Citation Index (ACI) - airiti1
- Policy Citations1
- Policy Citation1
- Captures520
- Readers520
- 520
- Mentions16
- References8
- Wikipedia8
- News Mentions7
- News7
- Blog Mentions1
- Blog1
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Article Description
The location of neurons generating the rhythm of breathing in mammals is unknown. By microsection of the neonatal rat brainstem in vitro, a limited region of the ventral medulla (the pre-Bötzinger Complex) that contains neurons essential for rhythmogenesis was identified. Rhythm generation was eliminated by removal of only this region. Medullary slices containing die pre-Bötzinger Complex generated respiratory-related oscillations similar to those generated by the whole brainstem in vitro, and neurons with voltage-dependent pacemaker-like properties were identified in this region. Thus, the respiratory rhythm in the mammalian neonatal nervous system may result from a population of conditional bursting pacemaker neurons in the pre-Bötzinger Complex.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0026360052&origin=inward; http://dx.doi.org/10.1126/science.1683005; http://www.ncbi.nlm.nih.gov/pubmed/1683005; https://www.science.org/doi/10.1126/science.1683005; https://dx.doi.org/10.1126/science.1683005; http://www.sciencemag.org/cgi/doi/10.1126/science.1683005; http://science.sciencemag.org/content/254/5032/726; http://science.sciencemag.org/content/254/5032/726.abstract; http://science.sciencemag.org/content/254/5032/726.full.pdf; http://science.sciencemag.org/cgi/doi/10.1126/science.1683005; https://www.science.org/doi/abs/10.1126/science.1683005; https://science.sciencemag.org/content/254/5032/726; https://science.sciencemag.org/content/254/5032/726.abstract; https://science.sciencemag.org/content/sci/254/5032/726.full.pdf; http://science.sciencemag.org/lookup/doi/10.1126/science.1683005
American Association for the Advancement of Science (AAAS)
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