PlumX Metrics
Embed PlumX Metrics

Wound repair and regeneration: Mechanisms, signaling, and translation

Science Translational Medicine, ISSN: 1946-6242, Vol: 6, Issue: 265, Page: 265sr6
2014
  • 2,273
    Citations
  • 0
    Usage
  • 2,829
    Captures
  • 7
    Mentions
  • 50
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    2,273
    • Citation Indexes
      2,261
    • Patent Family Citations
      12
      • Patent Families
        12
  • Captures
    2,829
  • Mentions
    7
    • News Mentions
      6
      • News
        6
    • Blog Mentions
      1
      • Blog
        1
  • Social Media
    50
    • Shares, Likes & Comments
      50
      • Facebook
        50

Most Recent News

Remote Continuous Microinjury-Triggered Cytokines Facilitate Severe Diabetic Foot Ulcer Healing via the Ras/Raf/MEK/ERK Pathway

Introduction Injury can trigger in situ tissue repair.1 Furthermore, microinjury can even mediate localized tissue regeneration without causing severe trauma or scarring.2 Bone transport, or

Review Description

The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are still poorly understood, and current therapies are limited. Poor wound healing after trauma, surgery, acute illness, or chronic disease conditions affects millions of people worldwide each year and is the consequence of poorly regulated elements of the healthy tissue repair response, including inflammation, angiogenesis, matrix deposition, and cell recruitment. Failure of one or several of these cellular processes is generally linked to an underlying clinical condition, such as vascular disease, diabetes, or aging, which are all frequently associated with healing pathologies. The search for clinical strategies that might improve the body's natural repair mechanisms will need to be based on a thorough understanding of the basic biology of repair and regeneration. In this review, we highlight emerging concepts in tissue regeneration and repair, and provide some perspectives on how to translate current knowledge into viable clinical approaches for treating patients with wound-healing pathologies.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know