Pterostilbene, a Potential MCR-1 Inhibitor That Enhances the Efficacy of Polymyxin B
Antimicrobial Agents and Chemotherapy, ISSN: 1098-6596, Vol: 62, Issue: 4
2018
- 49Citations
- 42Captures
- 1Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations49
- Citation Indexes49
- 49
- CrossRef25
- Captures42
- Readers42
- 42
- Mentions1
- News Mentions1
- 1
Most Recent News
Pterostilbene, a Potential MCR-1 Inhibitor That Enhances the Efficacy of Polymyxin B [Antiviral Agents]
Yonglin Zhou a , Shui Liu a , Tingting Wang a , Hui Li b , Shusheng Tang b , Jianfeng Wang a , Yang
Article Description
We characterized the synergistic effect produced between pterostilbene and polymyxin B (fractional inhibitory concentration [FIC] index = 0.156 or 0.188) against MCR-producing Escherichia coli strains of both human and animal origins. The time-killing assays showed that either pterostilbene or polymyxin B failed to eradicate the mcr-1- and NDM-positive E. coli strain ZJ487, but the combination eliminated the strain by 1 h postinoculation. The survival rate of mice after intraperitoneal infections was significantly enhanced from 0% to 60% in the group in which combination therapy was applied.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85044522255&origin=inward; http://dx.doi.org/10.1128/aac.02146-17; http://www.ncbi.nlm.nih.gov/pubmed/29339386; https://journals.asm.org/doi/10.1128/AAC.02146-17; http://aac.asm.org/lookup/doi/10.1128/AAC.02146-17; https://syndication.highwire.org/content/doi/10.1128/AAC.02146-17; https://dx.doi.org/10.1128/aac.02146-17
American Society for Microbiology
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