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Plasmodium falciparum and Plasmodium vivax genotypes and efficacy of intermittent preventive treatment in Papua New Guinea

Antimicrobial Agents and Chemotherapy, ISSN: 1098-6596, Vol: 58, Issue: 11, Page: 6958-6961
2014
  • 10
    Citations
  • 0
    Usage
  • 35
    Captures
  • 0
    Mentions
  • 38
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    10
  • Captures
    35
  • Social Media
    38
    • Shares, Likes & Comments
      38
      • Facebook
        38

Article Description

Intermittent preventive treatment of infants (IPTi) reduces early childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimalarial drugs in case management, there are few equivalent data relating to their protective efficacy when used as IPTi. The present data from an IPTi trial in Papua New Guinea demonstrate how these markers can predict protective efficacy of IPTi for both Plasmodium falciparum and Plasmodium vivax.

Bibliographic Details

Barnadas, Celine; Senn, Nicolas; Iga, Jonah; Timinao, Lincoln; Javati, Sarah; Malau, Elisheba; Rarau, Patricia; Reeder, John C; Siba, Peter; Karunajeewa, Harin; Zimmerman, Peter A; Davis, Timothy M; Mueller, Ivo

American Society for Microbiology

Pharmacology, Toxicology and Pharmaceutics; Medicine

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