Phenotypic changes in artemisinin-resistant Plasmodium falciparum lines in vitro: Evidence for decreased sensitivity to dormancy and growth inhibition
Antimicrobial Agents and Chemotherapy, ISSN: 0066-4804, Vol: 56, Issue: 1, Page: 428-431
2012
- 54Citations
- 67Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations54
- Citation Indexes54
- 54
- CrossRef52
- Captures67
- Readers67
- 67
Article Description
The appearance of Plasmodium falciparum parasites with decreased in vivo sensitivity but no measurable in vitro resistance to artemisinin has raised the urgent need to characterize the artemisinin resistance phenotype. Changes in the temporary growth arrest (dormancy) profile of parasites may be one aspect of this phenotype. In this study, we investigated the link between dormancy and resistance, using artelinic acid (AL)-resistant parasites. Our results demonstrate that the AL resistance phenotype has (i) decreased sensitivity of mature-stage parasites, (ii) decreased sensitivity of the ring stage to the induction of dormancy, and (iii) a faster recovery from dormancy. Copyright © 2012, American Society for Microbiology. All Rights Reserved.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84455170079&origin=inward; http://dx.doi.org/10.1128/aac.05456-11; http://www.ncbi.nlm.nih.gov/pubmed/21986828; http://aac.asm.org/lookup/doi/10.1128/AAC.05456-11; https://syndication.highwire.org/content/doi/10.1128/AAC.05456-11; https://journals.asm.org/doi/10.1128/AAC.05456-11; https://dx.doi.org/10.1128/aac.05456-11
American Society for Microbiology
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know