Amino Derivatives of Acridine: Synthesis and Study of Anticholinesterase and Antioxidant Activity
Doklady Chemistry, ISSN: 1608-3113, Vol: 509, Issue: 2, Page: 100-105
2023
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Article Description
Abstract: A simple and feasible approach to the synthesis of new amine derivatives of acridine based on the methodology of direct C–H functionalization has been developed. The inhibitory effect of the synthesized compounds toward cholinesterases and carboxylesterase as well as their antioxidant activity have been studied. A high anti-BChE activity has been shown for N-methylpiperazine derivative promising for further optimization to design on its basis new series of compounds efficient for the treatment of neurodegenerative diseases.
Bibliographic Details
Pleiades Publishing Ltd
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