Synthesis of new purine, pteridine, and other pyrimidine derivatives
Russian Journal of Organic Chemistry, ISSN: 1070-4280, Vol: 43, Issue: 3, Page: 443-448
2007
- 20Citations
- 13Captures
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Article Description
The reaction of malononitrile dimer with phenyl isothiocyanate gave (6-amino-1-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-ylidene)malononitrile which was then used as starting material in the synthesis of pharmacologically important fused pyrimidine derivatives, such as 4-dicyanomethylidene-1,5- diphenyl-2-thioxo-1,2,3,4-tetrahydropyrrolo[2,3-d]pyrimidine, 6-cyano-4-dicyanomethylidene-7-methylsulfanyl-5-oxo-1-phenyl-2-thioxo-1,2,3,4,5, 8-hexahydropyrido[2,3-d]pyrimidine, 6-dicyanomethylidene-3-phenyl-2-thioxo-1,2, 3,6-tetrahydro-9H-purine, and 6-substituted 4-dicyanomethylidene-7-oxo-1-phenyl- 2-thioxo-1,2,3,4,7,8-hexahydropteridines. © Nauka/Interperiodica 2007.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=34247364502&origin=inward; http://dx.doi.org/10.1134/s1070428007030219; http://link.springer.com/10.1134/S1070428007030219; http://link.springer.com/content/pdf/10.1134/S1070428007030219; http://link.springer.com/content/pdf/10.1134/S1070428007030219.pdf; http://link.springer.com/article/10.1134/S1070428007030219/fulltext.html; https://dx.doi.org/10.1134/s1070428007030219; https://link.springer.com/article/10.1134/S1070428007030219
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