Meta-analysis on inflammation and autonomic nervous system of coronary heart disease combined with depression
BMJ Open, ISSN: 2044-6055, Vol: 14, Issue: 3, Page: e079980
2024
- 2Citations
- 8Captures
- 3Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations2
- Citation Indexes2
- Captures8
- Readers8
- Mentions3
- News Mentions3
- News3
Most Recent News
Autonomic Nervous System and Sarcopenia in Elderly Patients: Insights from Long-Term Heart Rate Variability Monitoring in a Hospital Setting
Introduction Sarcopenia is a geriatric syndrome characterized by age-related loss of muscle mass, decreased muscle strength, and declined physical function. The prevalence of sarcopenia increases
Article Description
Objectives This meta-analysis aimed to explore the association between inflammatory factors, heart rate variability (HRV) and the coexistence of coronary heart disease (CHD) and depression. Design Systematic review and meta-analysis. Complying with the Meta-analysis Of Observational Studies in Epidemiology statement. Data sources We searched PubMed, Web of Science and EMBASE for the data from the inception date to 16 March 2023. Eligibility criteria We included cross-sectional and cohort studies with inclusion criteria: (1) patients with CHD; (2) depression measurement and (3) including inflammatory factors or cardiac biomarkers or HRV. Data extraction and synthesis Two authors searched the databases independently. The effect estimates and heterogeneity were synthesised by Review Manager V.5.3. Sensitivity analysis and publication bias were analysed by STATA software. The quantitative synthesis outcomes were presented by mean difference (MD) or standard MD (SMD) with 95% CI. Results By searching the databases, we identified a total of 6750 articles. There were 22 articles left after selection, including 6344 participants. This meta-analysis indicated that patients with CHD with depression had higher levels of C reaction protein (CRP) (SMD 0.50, 95% CI (0.19 to 0.81), p=0.001), high-sensitivity C reactive protein (hs-CRP) (SMD 0.28, 95% CI (0.07 to 0.48), p=0.008), IL-6 (SMD 0.49, 95% CI (0.05 to 0.92), p=0.03) and a lower level of the mean RR interval and the SD of all RR intervals (SMD −0.64, 95% CI (−1.11 to –0.17), p=0.008), SD of the 5 min averages of all normal RR intervals (MD −12.77 ms, 95% CI (–21.20 to –4.33), p=0.003), overage of the SD of all normal RR intervals for each 5 min segment (MD −13.83 ms, 95% CI (–15.94 to –11.72), p<0.00001), root mean square of successive differences (MD: −8.02 ms, 95% CI (–13.62 to –2.43), p=0.005), proportion of adjacent cycles differing by >50 ms (pNN50) (SMD −0.86, 95% CI (−1.41 to –0.31), p=0.002), than those without depression. Conclusions This study underscores the association between elevated CRP, hs-CRP, IL-6 and lower HRV in patients with CHD with depression. It emphasises the importance of clinicians assessing CRP, hs-CRP, IL-6 and HRV in patients with CHD to potentially identify depressive conditions.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85187179315&origin=inward; http://dx.doi.org/10.1136/bmjopen-2023-079980; http://www.ncbi.nlm.nih.gov/pubmed/38453204; https://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2023-079980; https://dx.doi.org/10.1136/bmjopen-2023-079980; https://bmjopen.bmj.com/content/14/3/e079980
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