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Society for immunotherapy of cancer (sitc) clinical practice guideline on immune checkpoint inhibitor-related adverse events

Journal for ImmunoTherapy of Cancer, ISSN: 2051-1426, Vol: 9, Issue: 6
2021
  • 447
    Citations
  • 0
    Usage
  • 361
    Captures
  • 8
    Mentions
  • 47
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    447
    • Citation Indexes
      443
    • Policy Citations
      3
      • Policy Citation
        3
    • Clinical Citations
      1
      • PubMed Guidelines
        1
  • Captures
    361
  • Mentions
    8
    • News Mentions
      7
      • News
        7
    • References
      1
      • Wikipedia
        1
  • Social Media
    47
    • Shares, Likes & Comments
      47
      • Facebook
        47

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Immune Checkpoint Inhibitor-Associated Nephritis: A Case of Nivolumab-Induced Acute Kidney Injury in a Patient with Urothelial Carcinoma

This case highlights the importance of recognizing ICPI-AKI, implementing effective therapeutic interventions, and understanding the clinical context to prevent irreversible renal damage. Introduction Immune checkpoint

Article Description

Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several cancers. While these immunotherapies have improved patient outcomes in many clinical settings, they bring accompanying risks of toxicity, specifically immune-related adverse events (irAEs). There is a need for clear, effective guidelines for the management of irAEs during ICI treatment, motivating the Society for Immunotherapy of Cancer (SITC) to convene an expert panel to develop a clinical practice guideline. The panel discussed the recognition and management of single and combination ICI irAEs and ultimately developed evidence- and consensus-based recommendations to assist medical professionals in clinical decision-making and to improve outcomes for patients.

Bibliographic Details

Brahmer, Julie R; Abu-Sbeih, Hamzah; Ascierto, Paolo Antonio; Brufsky, Jill; Cappelli, Laura C; Cortazar, Frank B; Gerber, David E; Hamad, Lamya; Hansen, Eric; Johnson, Douglas B; Lacouture, Mario E; Masters, Gregory A; Naidoo, Jarushka; Nanni, Michele; Perales, Miguel-Angel; Puzanov, Igor; Santomasso, Bianca D; Shanbhag, Satish P; Sharma, Rajeev; Skondra, Dimitra; Sosman, Jeffrey A; Turner, Michelle; Ernstoff, Marc S

BMJ

Medicine; Immunology and Microbiology; Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics

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