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Adult polycystic kidney disease and linked RFLPs at the α globin locus: A genetic study in the South Wales population

Journal of Medical Genetics, ISSN: 0022-2593, Vol: 24, Issue: 8, Page: 466-473
1987
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Article Description

Thirteen South Wales kindreds with adult polycystic kidney disease have been studied for genetic linkage using the α globin and 3'HVR probes. A maximum lod score of 24·187 was found at a recombination fraction of 0·03. This study supports the existence of a single locus on chromosome 16 responsible for the disorder.

Bibliographic Details

L. P. Lazarou; F. Davies; M. Sarfarazi; G. A. Coles; P. S. Harper

BMJ

Biochemistry, Genetics and Molecular Biology; Medicine

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