PLA/β-TCP complex tubes: The mechanical properties and applications of artificial bone
Journal of Biomaterials Science, Polymer Edition, ISSN: 0920-5063, Vol: 23, Issue: 13, Page: 1701-1712
2012
- 17Citations
- 16Captures
- 1Mentions
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- Citations17
- Citation Indexes17
- 17
- CrossRef1
- Captures16
- Readers16
- 16
- Mentions1
- News Mentions1
- News1
Most Recent News
Fused Deposition Modeling Printed PLA/Nano β-TCP Composite Bone Tissue Engineering Scaffolds for Promoting Osteogenic Induction Function
Wenzhao Wang,1,2,* Pan Liu,3,* Boqing Zhang,4 Xingyu Gui,4 Xuan Pei,5 Ping Song,2 Xia Yu,6 Zhengdong Zhang,7,8 Changchun Zhou4 1Department of Orthopaedics, Qilu Hospital of Shandong
Article Description
Poly(lactic acid) (PLA) twisted yarn was braided into a 6-layered, hollow, cylindrical braid on a 16-spindle braid machine. The PLA braid was then placed inside a β-TCP tube, forming the PLA/β-TCP complex tube which imitates the porous structure of sponge bone. Different components and structures were studied to determine the best bone molding material. The β-TCP tube was created by sintering TCP powder mixed with stearic acid in a ratio of 1:1.5 to form a highly porous and well-structured tube with interconnected pores; its resulting porosity was 85.8 ± 0.93%. The PLA/β-TCP complex tube was implanted in a rabbit's femur and after 3 months a marrow cavity was discovered at the tube's core. New bone was also observed, regenerating around the PLA braid within the PLA/β-TCP complex tube. © 2011 Koninklijke Brill NV, Leiden.
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