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Visual Analytics of Genomic and Cancer Data: A Systematic Review

Cancer Informatics, ISSN: 1176-9351, Vol: 18, Page: 1176935119835546
2019
  • 21
    Citations
  • 0
    Usage
  • 129
    Captures
  • 0
    Mentions
  • 36
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    21
  • Captures
    129
  • Social Media
    36
    • Shares, Likes & Comments
      36
      • Facebook
        36

Review Description

Visual analytics and visualisation can leverage the human perceptual system to interpret and uncover hidden patterns in big data. The advent of next-generation sequencing technologies has allowed the rapid production of massive amounts of genomic data and created a corresponding need for new tools and methods for visualising and interpreting these data. Visualising genomic data requires not only simply plotting of data but should also offer a decision or a choice about what the message should be conveyed in the particular plot; which methodologies should be used to represent the results must provide an easy, clear, and accurate way to the clinicians, experts, or researchers to interact with the data. Genomic data visual analytics is rapidly evolving in parallel with advances in high-throughput technologies such as artificial intelligence (AI) and virtual reality (VR). Personalised medicine requires new genomic visualisation tools, which can efficiently extract knowledge from the genomic data and speed up expert decisions about the best treatment of individual patient’s needs. However, meaningful visual analytics of such large genomic data remains a serious challenge. This article provides a comprehensive systematic review and discussion on the tools, methods, and trends for visual analytics of cancer-related genomic data. We reviewed methods for genomic data visualisation including traditional approaches such as scatter plots, heatmaps, coordinates, and networks, as well as emerging technologies using AI and VR. We also demonstrate the development of genomic data visualisation tools over time and analyse the evolution of visualising genomic data.

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