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Cracking the cement overcoat

Blood, ISSN: 0006-4971, Vol: 118, Issue: 15, Page: 4010-4012
2011
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Article Description

In this issue of Blood, Martires et al report on the risk factors for sclerotic skin manifestations in 206 patients with established chronic graft-versus-host disease (cGVHD). Sclerotic skin changes are one of the most dreaded manifestations of cGVHD, encasing the patients in unmovable skin. Patients become progressively immobilized in skin like layers of cement, making normal, daily living impossible (see figure).

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