The effect of text messaging on latent tuberculosis treatment adherence: A randomised controlled trial
European Respiratory Journal, ISSN: 1399-3003, Vol: 51, Issue: 2
2018
- 22Citations
- 147Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations22
- Citation Indexes22
- CrossRef22
- 19
- Captures147
- Readers147
- 147
Article Description
There is limited high-quality evidence available to inform the use of text messaging to improve latent tuberculosis infection (LTBI) treatment adherence. We performed a parallel, randomised controlled trial at two sites to assess the effect of a two-way short message service on LTBI adherence. We enrolled adults initiating LTBI therapy from June 2012 to September 2015 in British Columbia, Canada. Participants were randomised in a 1:1 ratio to standard LTBI treatment (control) or standard LTBI treatment plus two-way weekly text messaging (intervention). The primary outcome was treatment completion, defined as taking 80% prescribed doses within 12 months (isoniazid) or 6 months (rifampin) of enrolment. The trial was unblinded except for the data analyst. A total of 358 participants were assigned to the intervention (n=170) and control (n=188) arms. In intention-to-treat analysis, the proportion of participants completing LTBI therapy in the intervention and control arms was 79.4% and 81.9%, respectively (RR 0.97, 95% CI 0.88–1.07; p=0.550). Results were similar for pre-specified secondary end-points, including time-to-completion of LTBI therapy, completion of >90% of prescribed LTBI doses and health-related quality of life. Weekly two-way text messaging did not improve LTBI completion rates compared to standard LTBI care; however, completion rates were high in both treatment arms.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85052015189&origin=inward; http://dx.doi.org/10.1183/13993003.01488-2017; https://clinicaltrials.gov/ct2/show/NCT01549457; http://www.ncbi.nlm.nih.gov/pubmed/29437940; http://publications.ersnet.org/lookup/doi/10.1183/13993003.01488-2017; https://dx.doi.org/10.1183/13993003.01488-2017; https://erj.ersjournals.com/content/51/2/1701488
European Respiratory Society (ERS)
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