Management of esophageal stricture after complete circular endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma
BMC Gastroenterology, ISSN: 1471-230X, Vol: 11, Issue: 1, Page: 46
2011
- 130Citations
- 28Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations130
- Citation Indexes130
- 130
- CrossRef83
- Captures28
- Readers28
- 28
Article Description
Background: Endoscopic submucosal dissection (ESD) permits removal of esophageal epithelial neoplasms en bloc, but is associated with esophageal stenosis, particularly when ESD involves the entire circumference of the esophageal lumen. We examined the effectiveness of systemic steroid administration for control of postprocedural esophageal stricture after complete circular ESD.Methods: Seven patients who underwent wholly circumferential ESD for superficially extended esophageal squamous cell carcinoma were enrolled in this study. In 3 patients, prophylactic endoscopic balloon dilatation (EBD) was started on the third post-ESD day and was performed twice a week for 8 weeks. In 4 patients, oral prednisolone was started with 30 mg daily on the third post-ESD day, tapered gradually (daily 30, 30, 25, 25, 20, 15, 10, 5 mg for 7 days each), and then discontinued at 8 weeks. EBD was used as needed whenever patients complained of dysphagia.Results: En bloc ESD with tumor-free margins was safely achieved in all cases. Patients in the prophylactic EBD group required a mean of 32.7 EBD sessions; the postprocedural stricture was dilated up to 18 mm in diameter in these patients. On the other hand, systemic steroid administration substantially reduced or eliminated the need for EBD. Corticosteroid therapy was not associated with any adverse events. Post-ESD esophageal stricture after complete circular ESD was persistent, requiring multiple EBD sessions.Conclusions: Use of oral prednisolone administration may be an effective treatment strategy for reducing post-ESD esophageal stricture after complete circular ESD. © 2011 Isomoto et al; licensee BioMed Central Ltd.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79955510284&origin=inward; http://dx.doi.org/10.1186/1471-230x-11-46; http://www.ncbi.nlm.nih.gov/pubmed/21542926; https://bmcgastroenterol.biomedcentral.com/articles/10.1186/1471-230X-11-46; http://bmcgastroenterol.biomedcentral.com/articles/10.1186/1471-230X-11-46; http://link.springer.com/content/pdf/10.1186/1471-230X-11-46; http://link.springer.com/content/pdf/10.1186/1471-230X-11-46.pdf; http://link.springer.com/article/10.1186/1471-230X-11-46/fulltext.html; https://dx.doi.org/10.1186/1471-230x-11-46
Springer Science and Business Media LLC
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