PlumX Metrics
Embed PlumX Metrics

Genomic signatures of local adaptation in recent invasive Aedes aegypti populations in California

BMC Genomics, ISSN: 1471-2164, Vol: 24, Issue: 1, Page: 311
2023
  • 5
    Citations
  • 0
    Usage
  • 19
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Most Recent News

Researchers from University of California Davis Detail New Studies and Findings in the Area of Aedes aegypti (Genomic signatures of local adaptation in recent invasive Aedes aegypti populations in California)

2023 JUN 23 (NewsRx) -- By a News Reporter-Staff News Editor at Zika & Mosquito Daily -- Data detailed on Aedes aegypti have been presented.

Article Description

Background: Rapid adaptation to new environments can facilitate species invasions and range expansions. Understanding the mechanisms of adaptation used by invasive disease vectors in new regions has key implications for mitigating the prevalence and spread of vector-borne disease, although they remain relatively unexplored. Results: Here, we integrate whole-genome sequencing data from 96 Aedes aegypti mosquitoes collected from various sites in southern and central California with 25 annual topo-climate variables to investigate genome-wide signals of local adaptation among populations. Patterns of population structure, as inferred using principal components and admixture analysis, were consistent with three genetic clusters. Using various landscape genomics approaches, which all remove the confounding effects of shared ancestry on correlations between genetic and environmental variation, we identified 112 genes showing strong signals of local environmental adaptation associated with one or more topo-climate factors. Some of them have known effects in climate adaptation, such as heat-shock proteins, which shows selective sweep and recent positive selection acting on these genomic regions. Conclusions: Our results provide a genome wide perspective on the distribution of adaptive loci and lay the foundation for future work to understand how environmental adaptation in Ae. aegypti impacts the arboviral disease landscape and how such adaptation could help or hinder efforts at population control.

Bibliographic Details

Soudi, Shaghayegh; Crepeau, Marc; Collier, Travis C; Lee, Yoosook; Cornel, Anthony J; Lanzaro, Gregory C

Springer Science and Business Media LLC

Biochemistry, Genetics and Molecular Biology

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know