Status of gastric lavage in neonates born with meconium stained amniotic fluid: A randomized controlled trial

Background: Neonates born with meconium stained amniotic fluid (MSAF) can develop feed intolerance during first few days of post-natal period. A randomized controlled trial was conducted with the objectives of to find out the incidence of feed intolerance in vigorous neonates with MSAF who received gastric lavage (GL) as compared to those in whom it was not performed. Methods: This was a randomized controlled trial on 500 neonates satisfying the inclusion criteria, 230 were allocated to GL and 270 to no lavage group through computer generated random numbers. Results: No significant difference in the incidence of vomiting was found between GL and no lavage group (8.7 % vs 11.5 %, p = 0.305). Feed intolerance had no relationship with gestational age, gender, birth weight and mode of delivery. No neonates of GL group developed any complications related to the procedure. Conclusion: Thus, it may be concluded that gastric lavage is not required in neonates born with MSAF.