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Staphylococcus aureus surgical site infection rates in 5 European countries

Antimicrobial Resistance and Infection Control, ISSN: 2047-2994, Vol: 12, Issue: 1, Page: 104
2023
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Metric Options:   Counts1 Year3 Year

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Article Description

Objective: To determine the overall and procedure-specific incidence of surgical site infections (SSI) caused by Staphylococcus aureus (S. aureus) as well as risk factors for such across all surgical disciplines in Europe. Methods: This is a retrospective cohort of patients with surgical procedures performed at 14 European centres in 2016, with a nested case–control analysis. S. aureus SSI were identified by a semi-automated crossmatching bacteriological and electronic health record data. Within each surgical procedure, cases and controls were matched using optimal propensity score matching. Results: A total of 764 of 178 902 patients had S. aureus SSI (0.4%), with 86.0% of these caused by methicillin susceptible and 14% by resistant pathogens. Mean S. aureus SSI incidence was similar for all surgical specialties, while varying by procedure. Conclusions: This large procedure-independent study of S. aureus SSI proves a low overall infection rate of 0.4% in this cohort. It provides proof of principle for a semi-automated approach to utilize big data in epidemiological studies of healthcare-associated infections. Trials registration The study was registered at clinicaltrials.gov under NCT03353532 (11/2017).

Bibliographic Details

Mellinghoff, Sibylle C; Bruns, Caroline; Albertsmeier, Markus; Ankert, Juliane; Bernard, Louis; Budin, Sofia; Bataille, Camille; Classen, Annika Y; Cornely, Florian B; Couvé-Deacon, Elodie; Fernandez Ferrer, Maria; Fortún, Jesús; Galar, Alicia; Grill, Eva; Guimard, Thomas; Hampl, Jürgen A; Wingen-Heimann, Sebastian; Horcajada, Juan P; Köhler, Felix; Koll, Carolin; Mollar, Joan; Muñoz, Patricia; Pletz, Mathias W; Rutz, Jule; Salmanton-García, Jon; Seifert, Harald; Serracino-Inglott, Ferdinand; Soriano, Alex; Stemler, Jannik; Vehreschild, Janne J; Vilz, Tim O; Naendrup, Jan-Hendrik; Cornely, Oliver A; Liss, Blasius J

Springer Science and Business Media LLC

Medicine

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