In silico prediction and structure-based multitargeted molecular docking analysis of selected bioactive compounds against mucormycosis.
Bulletin of the National Research Centre, ISSN: 2522-8307, Vol: 46, Issue: 1, Page: 24
2022
- 8Citations
- 60Captures
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Metrics Details
- Citations8
- Citation Indexes8
- Captures60
- Readers60
- 60
Article Description
During the second wave of the COVID-19 pandemic, an unusual increase in cases of mucormycosis was observed in India, owing to immunological dysregulation caused by the SARS-CoV-2 and the use of broad-spectrum antibiotics, particularly in patients with poorly controlled diabetes with ketoacidosis to have contributed to the rise, and it has been declared an epidemic in several states of India. Because of the black colouring of dead and dying tissue caused by the fungus, it was dubbed "black fungus" by several Indian media outlets. In this study, attempts were taken to unmask novel therapeutic options to treat mucormycosis disease. species is the primary fungi responsible for 70% of mucormycosis cases.
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