Permeation of human plasma lipoproteins in human carotid endarterectomy tissues: measurement by optical coherence tomography
Journal of Lipid Research, ISSN: 0022-2275, Vol: 52, Issue: 7, Page: 1429-1434
2011
- 12Citations
- 11Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations12
- Citation Indexes12
- 12
- CrossRef8
- Captures11
- Readers11
- 11
Article Description
Atherosclerosis is an inflammatory process occurring in arterial tissue, involving the subintimal accumulation of LDL. Measurement of the rate at which LDL and other lipoproteins, such as HDL and VLDL, enter and exit the tissue can provide insight into the mechanisms involved in the development of atherosclerotic lesions. Permeation of VLDL, LDL, HDL, and glucose was measured for both normal and atherosclerotic human carotid endarterectomy tissues (CEA) at 20°C and 37°C using optical coherence tomography (OCT). The rates for LDL permeation through normal CEA tissue were (3.16 ± 0.37) × 10 −5 cm/s at 20°C and (4.77 ± 0.48) × 10 −5 cm/s at 37°C, significantly greater ( P < 0.05) than the rates for atherosclerotic CEA tissue at these temperatures [(1.97 ± 0.34) × 10 −5 cm/s at 20°C and (2.01 ± 0.23) × 10 −5 cm/s at 37°C]. This study effectively used OCT to measure the rates at which naturally occurring lipoproteins enter both normal and diseased carotid intimal tissue.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0022227520370371; http://dx.doi.org/10.1194/jlr.d015255; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79959209395&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/21508256; https://linkinghub.elsevier.com/retrieve/pii/S0022227520370371; http://www.jlr.org/lookup/doi/10.1194/jlr.D015255; https://syndication.highwire.org/content/doi/10.1194/jlr.D015255; https://dx.doi.org/10.1194/jlr.d015255
Elsevier BV
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