An emerging role for TOR signaling in mammalian tissue and stem cell physiology
Development, ISSN: 0950-1991, Vol: 138, Issue: 16, Page: 3343-3356
2011
- 116Citations
- 158Captures
- 3Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations116
- Citation Indexes116
- 116
- CrossRef92
- Captures158
- Readers158
- 158
- Mentions3
- References2
- Wikipedia2
- News Mentions1
- News1
Most Recent News
Mammalian target of rapamycin pathway is up-regulated by both acute endurance exercise and chronic muscle contraction in rat skeletal muscle
Introduction Skeletal muscle responds to periods of chronic contractile activity by increasing mitochondrial content, thereby improving fatigue resistance and contractile performance (Holloszy and Coyle 1984).
Review Description
The mammalian target of rapamycin (mTOR) is a kinase that responds to a myriad of signals, ranging from nutrient availability and energy status, to cellular stressors, oxygen sensors and growth factors. The finely tuned response of mTOR to these stimuli results in alterations to cell metabolism and cell growth. Recent studies of conditional knockouts of mTOR pathway components in mice have affirmed the role of mTOR signaling in energy balance, both at the cell and whole organism levels. Such studies have also highlighted a role for mTOR in stem cell homeostasis and lifespan determination. Here, we discuss the molecular mechanisms of TOR signaling and review recent in vitro and in vivo studies of mTOR tissuespecific activities in mammals. © 2011. Published by The Company of Biologists Ltd.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79960761944&origin=inward; http://dx.doi.org/10.1242/dev.058230; http://www.ncbi.nlm.nih.gov/pubmed/21791526; https://journals.biologists.com/dev/article/138/16/3343/44492/An-emerging-role-for-TOR-signaling-in-mammalian; https://dx.doi.org/10.1242/dev.058230; https://dev.biologists.org/content/138/16/3343; http://dev.biologists.org/content/138/16/3343; http://dev.biologists.org/content/138/16/3343.abstract; http://dev.biologists.org/content/138/16/3343.full.pdf; http://dev.biologists.org/cgi/doi/10.1242/dev.058230; https://dev.biologists.org/content/138/16/3343.abstract; https://dev.biologists.org/content/develop/138/16/3343.full.pdf; http://dev.biologists.org/lookup/doi/10.1242/dev.058230; http://europepmc.org/abstract/med/21791526; http://europepmc.org/articles/PMC3143559
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