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Eph/ephrin signalling during development

Development (Cambridge), ISSN: 1477-9129, Vol: 139, Issue: 22, Page: 4105-4109
2012
  • 171
    Citations
  • 0
    Usage
  • 289
    Captures
  • 4
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    171
  • Captures
    289
  • Mentions
    4
    • References
      3
      • Wikipedia
        3
    • Blog Mentions
      1
      • Blog
        1

Article Description

Eph receptors and their membrane-tethered ligands have important functions in development. Trans interactions of Eph receptors with ephrins at cell-cell interfaces promote a variety of cellular responses, including repulsion, attraction and migration. Eph-ephrin signalling can be bi-directional and controls actin cytoskeleton dynamics, thereby leading to changes in cellular shape. This article provides an overview of the general structures and signalling mechanisms, and of typical developmental functions along with cell biological principles. © 2012. Published by The Company of Biologists Ltd.

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