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The cell biology of mammalian fertilization

Development (Cambridge), ISSN: 0950-1991, Vol: 140, Issue: 22, Page: 4471-4479
2013
  • 145
    Citations
  • 0
    Usage
  • 400
    Captures
  • 4
    Mentions
  • 4
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    145
  • Captures
    400
  • Mentions
    4
    • News Mentions
      2
      • News
        2
    • References
      2
      • Wikipedia
        2
  • Social Media
    4
    • Shares, Likes & Comments
      4
      • Facebook
        4

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Article Description

Fertilization is the process by which eggs and spermatozoa interact, achieve mutual recognition, and fuse to create a zygote, which then develops to form a new individual, thus allowing for the continuity of a species. Despite numerous studies on mammalian fertilization, the molecular mechanisms underpinning the fertilization event remain largely unknown. However, as I summarize here, recent work using both gene-manipulated animals and in vitro studies has begun to elucidate essential sperm and egg molecules and to establish predictive models of successful fertilization. © 2013.

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