mazEF: A chromosomal toxin-antitoxin module that triggers programmed cell death in bacteria
Journal of Cell Science, ISSN: 0021-9533, Vol: 118, Issue: 19, Page: 4327-4332
2005
- 154Citations
- 248Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations154
- Citation Indexes153
- 153
- CrossRef135
- Patent Family Citations1
- Patent Families1
- Captures248
- Readers248
- 248
Article Description
mazEF is a toxin-antitoxin module located on the Escherichia coli chromosome and that of some other bacteria, including pathogens. mazF specifies for a stable toxin, MazF, and mazE specifies for a labile antitoxin, MazE, that antagonizes MazF. MazF is a sequence-specific mRNA endoribonuclease that initiates a programmed cell death pathway in response to various stresses. The mazEF-mediated death pathway can act as a defense mechanism that prevents the spread of bacterial phage infection, allowing bacterial populations to behave like multicellular organisms.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=27644590965&origin=inward; http://dx.doi.org/10.1242/jcs.02619; http://www.ncbi.nlm.nih.gov/pubmed/16179604; https://journals.biologists.com/jcs/article/118/19/4327/35164/mazEF-a-chromosomal-toxin-antitoxin-module-that; https://dx.doi.org/10.1242/jcs.02619; https://jcs.biologists.org/content/118/19/4327
The Company of Biologists
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