Facile Preparation of Peptides with C-Terminal N-Alkylamide via Radical-Initiated Dethiocarboxylation
Chemical and Pharmaceutical Bulletin, ISSN: 1347-5223, Vol: 64, Issue: 4, Page: 375-378
2016
- 3Citations
- 9Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations3
- Citation Indexes3
- CrossRef1
- Captures9
- Readers9
Article Description
A new synthetic method has been developed to prepare peptides bearing a C- Terminal N- Alkylamide from peptide thioacids via a radical-initiated dethiocarboxylation process. This method enables the introduction of various alkyl groups to C- Terminal amides simply by replacing the amino acid building block. Its application to the preparation of anti-cancer drug ABT-510 is also reported.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84964768936&origin=inward; http://dx.doi.org/10.1248/cpb.c15-01025; http://www.ncbi.nlm.nih.gov/pubmed/27039836; https://www.jstage.jst.go.jp/article/cpb/64/4/64_c15-01025/_article; https://dx.doi.org/10.1248/cpb.c15-01025; https://www.jstage.jst.go.jp/article/cpb/64/4/64_c15-01025/_article/-char/en/; https://www.jstage.jst.go.jp/article/cpb/64/4/64_c15-01025/_article/-char/ja/
Pharmaceutical Society of Japan
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